Balevi B. Colgate Sensitive Pro Relief Whitening for improved stain removal. Colgate Sensitive Instant Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. YYYY Colgate-Palmolive Company. Tel: +381 (0)21 452-910, +381 (0)21 420-758. The benefits are backed by over a decade of clinical research, summarized as follows. 29,95 kr. J Dent. The mean scores with repeated measures were statistically analysed at each time point for study outcomes. 1). Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. volume21, Articlenumber:498 (2021) The widely accepted hydrodynamic theory proposes that stimuli can alter the behavior of fluid in the dentin tubules, activating intra-dental nerve fibers and causing pain. Clin Cosmet Investig Dent. Follow the directions for use. Lasting protection with regular use. This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste contains Sodium Fluoride (1450ppmF) the recommended fluoride level for effective caries prevention.4. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. [18] in a meta-analysis in 2020. Am J Dent. 2015;28(1):404. YYYY Colgate-Palmolive Company. It is clinically proven for instant and lasting Sensitivity relief* How does it work? Providing effective solutions for this prevalent condition is a priority for every dental professional, and Colgates Pro-Argin technology is helping dentists lead the way. Arshad, S., Zaidi, S.J.A. YES Somewhat No *Fr omedelbar lindring ska du applicera direkt p den knsliga . Am J Dent. It contains clinically proven Pro-Argin technology which provides instant and lasting sensitivity relief. *with direct application and daily brushing. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste delivers instant* and long-lasting sensitivity relief plus gum protection. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. Colgate Sensitive Instant Relief Multiprotection Toothpaste gives you clinically proven lasting relief from sensitivity for 8 weeks when you use it twice a day. The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. Post-application changes on SCASS were observed after one minute, three days, two, four, and six weeks, subsequently. who examined FCPS and Pro-argin formulations in 2018. Clinically proven lasting relief for 8 weeks. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. IADR, The Excel, United Kingdom. Therefore, it was considered to be rejected at a p valueof 0.05. J Clin Dent 20 (2009), special issue 17-22, 3. Lg i kurv. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 Free postage. The burden of dentine hypersensitivity. Another study by Hines et al. The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. 2. Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. and Ayad et al. Colgate Sensitive PRO-Relief Provides clinically proven, everyday protection from painful sensitivity. HOW LONG CAN A PATIENT USE Colgate SENSITIVE INSTANT Relief Repair & Prevent? Mintsmak. In comparison, the Pro-argin can make mechanical barrier of calcium phosphate precipitates on exposed dentinal tubules up to 2m depth by the interaction of positively charged arginine, amino acids and type 1 collagen fibres [8]. 1). The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. Cunha-Cruz J, Wataha JC. 2017;30(4):2216. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. Not all desensitizing toothpastes perform equally well. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. Ashwini S, Swatika K, Kamala DN. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. Get the best deals for COLGATE Sensitive Pro Relief Complete Protection Toothpaste 110g. Colgate Sensitive Pro Relief Teeth Whitening Sensitivity Toothpaste, 75ml 4.9 out of 5 stars 12 7 offers from SAR 33.95 Colgate Sensitive Pro Relief Base Instant Sensitivity Relief Toothpaste, 75ml 4.3 out of 5 stars 20 5 offers from SAR 31.25 Colgate Total 12 hour Protection Pro - Gum Health Toothpaste 75ml 2. Colgate Total with stannous fluoride also offers more benefits than ever before, including sensitivity relief, improved enamel strength* and odor neutralization* (*based on in vitro studies).Colgate Total Advanced Whitening is a tooth whitening toothpaste that provides stain removal and prevention. J Dent. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. [8] that demonstrated the inherent ability of chemical interaction between arginine and type 1 collagen molecules in the salivary alkaline PH, thus resulting in endogenous calcium phosphate deposition on exposed dentinal tubules. Builds a protective barrier that acts like . PubMed After six weeks, FCPS-based dentifrices showed greater clinical efficacy with mean scores (1.801.73) than other treatment arms for waterjet stimulated DH. 2018;9(3):3306. J Clin Dent. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. J Clin Exp Dent. In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. Google Scholar. Table 5 presents the change in the mean scores of VAS against mechanical stimulus from baseline to subsequent efficacy interval within each treatment arm. Colgate Tandpasta Sensitive Instant Relief Whitening. J Clin Dent 2009; 20 (Spec Iss): 17-22. The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. The statistician was also kept blinded. Product Information. Product Details Page . Canines and premolars are the most commonly affected teeth among 2530% of the adult population [2]. In addition, participants were asked to record the overall sensitivity of their day-to-day experience on provided VAS sheets reporting pain on brushing, taking hot or cold beverages, and rinsing with tap water for the six weeks of the study. J Dent Res. Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an 8-week clinical study. 2009;20(1):106. Dentine hypersensitivity (DH) is a chronic condition with acute, transient pain in non-carious teeth that originates in response to thermal stimuli such as hot or cold, chemicals like acidic or sweet or salt, and mechanical stimuli due to exposure to dentinal tubules without any apparent clinical disease [1]. PubMed SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? Grading of Recommendations, Assessment, Development and Evaluations. Read our disclaimer for details. They explored greater tubular occlusion potential and more acid resistance of Pro-argin in comparison to FCPS after subsequent seven days of application on dentinal discs [38]. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. 3Intervention for Group C denotes Sensodyne Rapid Action. Gently and effectively removes stains. Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. Hu M-L, Zheng G, Zhang Y-D, Yan X, Li X-C, Lin H. Effect of desensitizing toothpastes on dentine hypersensitivity: a systematic review and meta-analysis. Docimo et al. J Clin Dent. 1. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Listing a study does not mean it has been evaluated by the U.S. Federal Government. These toothpaste Moreover, the occluding potential of Pro-argin has also been ascertained in a previous in vitro analysis conducted by Lavender et al. Trials. 2010;23(Spec No A):14A-9A. If symptoms persist, talk to your healthcare professional. J Clin Periodontol. 2012;12(3):2208. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. How to use SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. With the exclusive Pro-Argin formula, it provides instant* and lasting** relief by plugging the channels to block tooth sensitivity. It effectively occludes open dentine tubuli instantly* and builds a strong calcium-rich layer that ensures long-lasting relief from the pain of sensitivity.1,2 The protective layer remains strong even after exposure to acid attacks.3, of respondents confirmed reduced dentine hypersensitivity with Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents were happy with their dentists recommending Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents noticed long-lasting and instant* relief when brushing with Colgate SENSITIVE INSTANT Relief toothpaste7,, Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief. 1997;24(11):80813. Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. For best performance, keep cap closed when not in use. 2013;41:S317. 1). Privacy To alleviate their tooth sensitivity problem, by using Colgate Sensitive Pro-Relief will give them lasting relief and they can drink ice water freely. 2010;21(2):428. Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. PubMed Central In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6. Colgate Sensitive Pro Relief Multi Protection, offering all of the above benefits in one convenient formula. J Clin Dent. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. in 2018 [17]. Mockdeci H, Polonini H, Martins I, Granato A-P, Raposo N. Evaluation of ex vivo effectiveness of commercial desensitizing dentifrices. In vitro analysis suggested that FCPS-based dentifrice enabled the slow and sustained release of fluoride contents, resulting in more stable fluorapatite crystals in saliva [14, 15]. Product Benefits. Colgate Sensitive Pro-Relief Enamel Repair contains Pro-Argin formula, helping to remineralise enamel, strengthen teeth against acid in food and drinks, plus instantly plugs channels to sensitive nerves. Directions for Use: For instant relief, apply directly to the sensitive tooth with finger tip and massage gently for 1 minute, up to twice a day and for children 6-12 years once a week or less frequently. For lasting relief and gum protection, apply twice daily using a sensitive toothbrush, making sure to brush all surfaces of teeth including sensitive areas. WHAT IS Colgate SENSITIVE INSTANT Relief Repair & Prevent? The formula consists of Arginine, an amino acid naturally found in saliva and also calcium from calcium carbonate. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Poster #3406, July 2018 IADR. These fluorapatite crystals were less susceptible to acidic dissolution than hydroxyapatite crystals and thus were more desirable [13]. 1997;24(11):80813. Helps restore natural whiteness of teeth. . Pessoa OF, Loretto SC, Maia LC. When you recommend Colgate Sensitive Pro Relief, you can help your dentin hypersensitivity patients to enjoy a pain-free life, confident in the knowledge that youre providing a highly effective, evidence-based solution. 2017;71:18. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. Statistical Package for the Social Sciences software v.21.0. Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! Colgate Sensitive Pro-Relief (Toothpaste): 1.9 out of 5 stars from 91 genuine reviews on Australia's largest opinion site ProductReview.com.au. Shiau HJ. Follow the directions for use. Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. Colgate-Palmolive Company 2018. Poster #0742, March 2018 AADR. A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. They reported more clinical efficacy with BioMin than Pro-argin reduction in air-blast stimulated DH on VAS after one month [39]. Lai et al. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. Samueli A, Hill R, Gillam D. Bioactive glasses in the management of dentine hypersensitivity: a review. Was this answer helpful? Dentine hypersensitivity. A previously published study by Samueli et al. Ingredients *Calcium carbonate *Water in 2019 using BioMin F and Pro-argin. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26]. Another study by Hines et al. Another . Dentin hypersensitivity. 2019;88:103170. They don't. This clinical trial was approved by the Institutional Review Board of Dow University of Health Sciences (Ref: IRB-1351/DUHS/Approval/2019/184) and was registered under the protocol ID NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336) on January 30, 2020, in accordance with the CONSORT statement of the updated guidelines for reporting randomised clinical trials. * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. Directions Madurai: Best Dental Science College; 2020. 2016;27(4):916. Part of [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. 5 Hines D et al. Therefore, the current study outcomes were analysed by parametric and non-parametric statistical tests after assessing the normal distribution of data and equality of variances with Shapiro Wilk statistics. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. All the treatment groups subjected to testing in the present study revealed a considerable clinically significant symptomatic reduction in DH relative to the pre-treatment condition that was also statistically significant. Colgate Sensitive Pro-Relief toothpastes have been formulated to provide instant and lasting relief from the pain associated with sensitive teeth. Then, the repeated measure was obtained after five minutes for previous pain recovery, and dentifrices were provided to the patient for self-application. ID: NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336), Date of Registration: January 30, 2020 (Retrospectively registered). Participantswere strictly advised to refrain from acidic food and drink intake at least four hours before following up visit. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. 2020;12(2):87. Contemp Clin Dent. 6 Ipsos, Romania Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2-week trial, 545 respondents, 2015. Written consent was obtained from all participants to participate in the six-week clinical trial. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. Correspondence to The statistically significant change in mean scores of DH was observed with FCPS with p<0.05 relative to baseline for sustained relief from DH at follow-ups on day 3, week 2, week 4, and week 6, using clinical parameters of SCASS and VAS. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. These outcomes were found in concordance with the previous controlled clinical trial conducted by Patel et al. Docimo R, Montesani L, Maturo P, Costacurta M, Bartolino M, DeVizio W, Zhang YP, Cummins D, Dibart S, Mateo LR: Comparing the Efficacy in Reducing Dentine Hypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride to a Commercial Sensitive Toothpaste Containing 2% Potassium Ion: An Eight-Week Clinical Study in Rome, Italy. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. Am J Dent. All rights reserved. While 8% strontium acetate showed a greater clinical reduction in water jet stimulated DH on VAS than Pro-argin at all efficacy intervals, as demonstrated in Table 6. 2017;2017:2. Provides 24/7 sensitivity protection. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. 2017;2017:2. All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Mahmoodi B, Wood R, Cook R. Protection and acid resistivity of bioactive-glasses, arginine and calcium silicate. Modified bass brushing method was demonstrated on the same model before the first application of dentifrices in the dental clinic. PREVENTS SENSITIVITY COMING BACK: Sealed channels protect against pain for instant relief, and with regular use provide lasting protection to prevent sensitivity from . J Dent. Docimo R et al. KruskalWallis test was used to compare treatment groups. Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial. Pro-Argin technology helps to seal and repair . Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. Many patients tolerate the pain of sensitive teeth because theyre unaware of simple but highly effective answers like Pro-Argin technology. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. These then interact to form a complex with positive charge. The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH.